FUSION BODYBUILDING

Bodybuilding’s Strongest Supplements

AGENT•M Powder
Grape-Flavoured Progressive BCAA Powder

Supplement Facts

Serving Size: 1 Rounded Scoop

Servings Per Container: 20

Amount Per Serving % Daily Value
Muscle Mechanic® Complex 12,000 mg
L-Leucine (BCAA 2:1:1) [2-amino-4-methylpentanoic acid] 5,500 mg
L-IsoLeucine (BCAA 2:1:1) [2-amino-3-methylvaleric acid] 2,750 mg
L-Valine (BCAA 2:1:1) [2-amino-3-methylbutanoic acid] 2,750 mg
L-Arginine [2-amino-5-guanidinopentanoic acid] 1000 mg
Muscle Inflamation™ Complex 250 mg
M•ZYME®
Systemic Enzyme Blend
[Protease (6.0) (conc.) 22,222 HUT, Peptidase 11,111 HUT, Protease (4.5) 33,333 HUT, Bromelain 555,555 FCCPU, Papain 69,444 FCCPU, Rutin 50 mg, Amla Berry 50 mg]
Muscle Support Complex 56.8 mg
Magnesium Citrate 30 mg
Vitamin B1 (Thiamine Hydrochloride) 5 mg
Vitamin B2 (Riboflavin) 5 mg
Vitamin B3 (Niacinamide) 5 mg
Vitamin B5 (D-Calcium Panothenate) 5 mg
Vitamin B6 (Pyridoxine Hydrochloride) 5 mg
Vitamin B9 (Folic Acid) 5 mg
Vitamin B12 (Cyanocobalamin) 5 mg
Absorption Initiator 3 mg
Bioperine® Piper nigrum (Black Pepper) (fruit)
[Standardized for 95% piperine]

Daily Value Not Established

Ingredients

Muscle Mechanic® Complex – 12,000 mg

Branched-Chain Amino Acids

Branched-chain amino acids (BCAAs) consist of leucine, isoleucine and valine. Branched-chain amino acids stimulate protein synthesis and muscle growth.1

During exercise, BCAAs keep your testosterone levels high and give you energy, and this prevents muscle breakdown during exercise.2 BCAAs also give you more energy by triggering the release of norepinephrine, so you can work harder and to your full limit.3

After a workout, BCAAs speed your recovery by triggering insulin release4 and reducing pain and muscle inflammation,5 ultimately pushing you back into a muscle-building anabolic state.6

Arginine

Arginine, an amino acid that produces nitric oxide and muscle pumps, is highly effective and works in synergy with BCAAs to dramatically stop muscle breakdown cold.7

Muscle Inflammation™ Complex – 250 mg

M•ZYME®

M•ZYME’s specialized systemic enzymes are clinically proven to make your immune system stronger8 and to dramatically speed your recovery, getting you bigger and faster in record time!9

After a hard workout, pro-inflammatory chemicals prostaglandin E-2 (PGE-2) and interleukin-6 (IL-6) amplify the inflammation caused by a hard workout, and this causes excessive cortisol release – and muscle breakdown.

M•ZYME’s specialized systemic enzymes are proven to decrease PGE-2 and IL-6 activity,4,2 and this leads to dramatically lower cortisol secretions and an astounding 65% reduction of inflammation.10 This helps prevent delayed onset muscle soreness (D.O.M.S.) and ensures that you keep the muscle you have and build more faster than ever!

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Muscle Support Complex – 26.8 mg

Magnesium Citrate
Magnesium is important for hundreds of bodily processes and is fundamental for the functioning of muscles. Magnesium Citrate also increase the muscle cells’ ATP/ADP ratio. Magnesium attaches to ATP stabilizing the molecule allowing it to be stored as a source of energy that can be utilized by muscle cells.
Vitamin B1 – Thiamine Hydrochloride

Isolated and characterized in the 1930s, thiamin was one of the first organic compounds recognized as a vitamin. Thiamin occurs in the human body as free thiamine, and one of its forms, thiamin pyrophosphate (TPP), is a required coenzyme for a small number of very important enzymes. These enzymes play critical roles in the production of energy from food, including catalyzing branched-chain amino acids.

Vitamin B2 – Riboflavin

In the body, riboflavin is an integral component of key coenzymes. Coenzymes derived from riboflavin are termed flavocoenzymes, and enzymes that use a flavocoenzyme are called flavoproteins. Living organisms derive most of their energy from oxidation-reduction (redox) reactions. Flavocoenzymes are critical for the metabolism of carbohydrates, fats and proteins. The coenzyme derived from riboflavin called flavin adenine dinucleotide (FAD) is part of the electron transport (respiratory) chain, which is central to energy production. FAD is also a critical coenzyme in the regeneration of glutathione, therefore playing a major role as an antioxidant.

Vitamin B3 – Niacinamide

Niacin is a water-soluble vitamin also known as nicotinic acid. It is used to form the coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP). As many as 200 enzymes require the niacin coenzymes NAD and NADP. NAD functions most often in energy-producing reactions involving carbohydrates, fats, proteins and alcohol. NADP functions more often in biosynthetic reactions, such as in the synthesis of all macromolecules.

Vitamin B5 – D-Calcium Pantothenate

Vitamin B5 is essential to all forms of life. It is found throughout living cells in the form of coenzyme A (CoA). CoA is required for chemical reactions that generate energy from food (fat, carbohydrates and proteins). The synthesis of essential fats, cholesterol and steroid hormones requires CoA, as does the synthesis of the neurotransmitter acetylcholine and the hormone melatonin. Heme, a component of hemoglobin, requires a CoA-containing compound for its synthesis. The liver requires CoA to metabolize many drugs and toxins.

Vitamin B6 – Pyridoxine Hydrochloride

Vitamin B6 is a water-soluble vitamin that was first isolated in the 1930s. The principal coenzyme form, pyridoxal 5'-phosphate (PLP), has the most importance in human metabolism. PLP plays a vital role in the function of approximately 100 enzymes that catalyze essential chemical reactions in the human body. For example, PLP functions as a coenzyme for glycogen phosphorylase, an enzyme that catalyzes the release of glucose from stored glycogen. Glycogen stored in muscle is used as an energy reserve that can be quickly mobilized to meet a sudden need for glucose. Much of the PLP in the human body is found in muscle bound to glycogen phosphorylase. PLP is also a coenzyme for reactions used to generate glucose from amino acids, a process known as gluconeogenesis.

Vitamin B9 – Folic Acid

The terms folic acid and folate are often used interchangeably for this water-soluble B-complex vitamin. Folate coenzymes act in a variety of reactions critical to the metabolism of nucleic acids and amino acids. Folate coenzymes play a vital role in DNA metabolism. Folate coenzymes are required for metabolizing several important amino acids.

Vitamin B12 – Cyanocobalamin

Vitamin B12 has the largest and most complex chemical structure of all the vitamins. It is unique among vitamins in that it contains a metal ion, cobalt. For this reason, cobalamin is the term used to refer to compounds having vitamin B12 activity. It is a cofactor for only two enzymes, methionine synthase and L-methylmalonyl-CoA mutase. Methylcobalamin is required for the function of the folate-dependent enzyme methionine synthase. This enzyme is required for synthesizing the amino acid methionine from homocysteine. L-methylmalonyl-CoA mutase helps play an important role in the production of energy from fats and proteins.

Absorption Initiator – 3 mg

Bioperine® Piper nigrum (Black Pepper)
Bioperine contains 95% piperine. Piperine is clinically proven to give you more bang for your buck by increasing enzyme absorption and effectiveness by as much as 60%.11

Other Ingredients

Natural flavours, citric acid, trisodium citrate, red beet powder, sucralose, soy lecithin, silicon dioxide, acesulfame potassium, FD&C Blue #1

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SCIENTIFIC REFERENCES

  1. Blomstrand E., et al (2006 January). Branched-chain amino acids activate key enzymes in protein synthesis after physical exercise. J Nutr, 136(1 Suppl),269S-73S.
  2. Kraemer W. J., et al (2006 March). The effects of amino acid supplementation on hormone responses to resistance training overreaching. Metabolism, 55(3),282-91.
  3. Torigoe K., Potter P. E., Katz D. P. (1999). Branched-chain amino acid-induced hippocampal norepinephrine release is antagonized by picrotoxin: Evidence for a central mode of action. Brain Res Bull, 49(4), 281-284, (31 ref).
  4. Keller C., Steensberg A., Hansen A. K., Fischer C. P., Plomgaard P., Pedersen B. K. (2005 December). Effect of exercise, training, and glycogen availability on IL-6 receptor expression in human skeletal muscle. J Appl Physiol, 99(6), 2075-9. Epub 2005 Aug 11.
  5. Papers presented at the American College of Sports Medicine annual meeting, June 2007.
  6. Paddon-Jones D., et al (2004 March). Amino acid ingestion improves muscle protein synthesis in the young and elderly. Am J Physiol Endocrinol Metab, 286(3), E321-8.
  7. Matsumoto K., et al (2007). Branched-chain amino acids and arginine supplementation attenuates skeletal muscle proteolysis induced by moderate exercise in young individuals. Int J Sports Med, 28, 531-538.
  8. Paddon-Jones D., et al (2003 May). Hypercortisolemia alters muscle protein anabolism following ingestion of essential amino acids. Am J Physiol Endocrinol Metab, 284(5), E946-53.
  9. Vellini M., Desideri D., Milanese A., et al (1986). Possible involvement of eicosanoids in the pharmacological action of bromelain. Drug Res, 36, 110-112.
  10. Miller P. C., et al (2004). The effects of protease supplementation on skeletal muscle function and D.O.M.S. following downhill running. J Sport Sci, 22, 365-372.
  11. Velpandian T., Jasuja R., Bhardwaj R. K., Jaiswal J., Gupta S. K. (2001 October). Piperine in food: interference in the pharmacokinetics of phenytoin. Eur J Drug Metab Pharmacokinet, 26(4), 241-7.