GLUTAMEND™ was scientifically formulated to deliver appreciable, reliable results. Each ingredient was chosen for its research-proven ability to help bodybuilders like you to achieve results.

L-Glutamine – 5,000 mg

Glutamine is the most abundant amino acid in the human body, and it makes up approximately 60 percent of the total free amino acid pool.¹ Glutamine is classified as a non-essential amino acid for the general population and a semi-essential amino acid for athletes. Training volume, frequency and intensity determine each bodybuilder’s individual glutamine requirements. Scientific consensus supports glutamine supplementation for bodybuilders and athletes who train intensely and frequently.

Glutamine is used to manufacture glucose in your liver from free amino acids via a process called gluconeogenesis. Because glutamine is the most present amino acid in human blood and is the predominant free amino acid pool constituent, it’s the amino acid of choice for glucose creation. This makes it a bodybuilder’s first line of defense against the muscle-tissue breakdown that typically follows glycogen and glucose depletion and deficit following hard training. Research shows that intense bodybuilding training depletes glutamine concentrations by as much as 40 percent, pushing most bodybuilders into a state of deficiency and muscle catabolism.² Glutamine supplementation helps offset these harmful effects.

Glutamine is also important in several key metabolic processes of the immune system. Added glutamine augments the functions of the white blood cells lymphocytes and macrophages, and it increases the bacterial killing function of the most abundant type of white blood cells, neutrophils. Glutamine is thought to be useful for preventing and treating severe infection in critical illness and trauma.³

Glutamine aids in anabolism and muscle growth – two related but separate processes – by maintaining positive nitrogen balance and stimulating growth hormone release.⁴ In addition to its hormonal effects on growth hormone, research shows that glutamine also exerts direct anabolic activity by fueling muscle fiber division and growth of up to 400 percent in even the most challenging physical conditions.⁵

In addition to offsetting catabolism resulting from insufficient levels of available glutamine, glutamine supplementation also aids anabolism and muscle growth by enhancing digestive efficiency. Glutamine is important for your intestines’ health and function.⁶ It’s the principal fuel for cells in the small intestine, and use of glutamine supplements has been shown to increase the number and size of intestinal cells.⁷ Healthy intestines mean better digestion, and better digestion increases caloric and nutrient yield. By enhancing digestive efficiency and increasing total nutrient extraction, glutamine dramatically speeds recovery and muscle growth, simultaneously initiating tissue repair at the muscle site.⁸

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Muscle Function Complex – 249 mg

Calcium carbonate – 177 mg

Calcium is essential for correct nerve function and muscular contraction. Calcium plays an essential role in nerve function and nerve-firing mediation and therefore aids the muscle-building action of glutamine. Whereas calcium aids in muscle contraction, glutamine follows up to maximize that contraction through providing the optimal anabolic environment. Animal research suggests that calcium further aids glutamine activity by mediating nerve function and brain glutamine usage.⁹ Calcium also aids in maintaining bone, the underlying skeletal structure upon which you build muscle. Strong bones support strong, functional muscles.

Magnesium citrate – 70 mg

Magnesium aids muscle growth by fueling new cell formation, activating B vitamin activity and increasing circulation and digestive efficiency, and it plays a role in generating adenosine triphosphate (ATP), the fuel source for cells. Magnesium and calcium work together to mediate muscular contraction and nerve responses to exercise. While calcium is critical for the transmission of nerve signals and muscular contraction, magnesium works to induce a relaxed muscle response. Research supports magnesium citrate as the ideal form of magnesium for supplementation, as it’s quickly absorbed.¹⁰ By aiding digestion, activating anabolic B vitamins and mediating muscle function, magnesium aids in protein synthesis and the construction of new muscle tissue.¹¹

Vitamin D₃ – 2 mg

Vitamin D₃ is essential for hormone manufacture and for maintaining a strong cardiovascular system, a system that circulates oxygen and nutrients to your hard-working muscles. Vitamin D₃ helps sustain high levels of blood calcium, ensuring correct muscular contraction to fuel and sustain increasingly intense muscular activity over progressively long periods of time. By helping sustain blood calcium levels, Vitamin D₃ increases workout performance and your total muscular endurance capacity.

Absorption Initiator – 1 mg

Bioperine^® Piper nigrum (Black Pepper)

The amount of a supplement absorbed can be low for various factors, including sex, age, personal fitness and health profile, and more. For example, research shows that the oral absorption rate of enzymes is low, at approximately 40 percent.¹² Other supplement ingredients can have similar absorption rates. Bioperine®, which contains piperine, can enhance the absorption rate of all supplements dramatically. One study shows that piperine increases the absorption of selected supplement ingredients in humans by as much as 65 percent.¹³

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